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1

ChemInform Abstract: Identification of (-)-cis-6-Acetyl-4S- (3-chloro-4-fluorobenzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo [b]pyran-3S-ol (I) as a Potential Antimigraine Agent.

Wai N. Chan, John M. Evans, Michael S. Hadley, Hugh J. Herdon, Jeffrey C. Jerman, Andrew A. Parsons, Simon J. Read, Tania O. Stean, Mervyn Thompson, Neil Upton

Journal:

Year:

1999

File:

PDF, 28 KB

1999

2

Discovery of small molecule antagonists of TRPV1

Harshad K Rami, Mervyn Thompson, Paul Wyman, Jeffrey C Jerman, Julie Egerton, Stephen Brough, Alexander J Stevens, Andrew D Randall, Darren Smart, Martin J Gunthorpe, John B Davis

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 339 KB

english, 2004

3

N-Tetrahydroquinolinyl, N-quinolinyl and N-isoquinolinyl biaryl carboxamides as antagonists of TRPV1

Susan M. Westaway, Ying-Kit Chung, John B. Davis, Vicky Holland, Jeffrey C. Jerman, Stephen J. Medhurst, Harshad K. Rami, Geoffrey Stemp, Alexander J. Stevens, Mervyn Thompson, Kim Y. Winborn, James W

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 121 KB

english, 2006

4

Structure–activity analysis of truncated orexin-A analogues at the orexin-1 receptor

John G Darker, Roderick A Porter, Drake S Eggleston, Darren Smart, Stephen J Brough, Cibele Sabido-David, Jeffrey C Jerman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 109 KB

english, 2001

5

1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor

Roderick A Porter, Wai N Chan, Steven Coulton, Amanda Johns, Michael S Hadley, Katherine Widdowson, Jeffrey C Jerman, Stephen J Brough, Martyn Coldwell, Darren Smart, Frances Jewitt, Phillip Jeffrey,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 131 KB

english, 2001

6

Identification of a series of 1,2,3,4-tetrahydroisoquinolinyl- benzamides with potential anticonvulsant activity

Wai N. Chan, Michael S Hadley, John D. Harling, Hugh J. Herdon, Jeffrey C. Jerman, Barry S. Orlek, Tania O. Stean, Mervyn Thompson, Neil Upton, Robert W. Ward

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 218 KB

english, 1998

7

Identification of (−)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent

Wai N. Chan, John M. Evans, Michael S Hadley, Hugh J. Herdon, Jeffrey C. Jerman, Andrew A. Parsons, Simon J. Read, Tania O. Stean, Mervyn Thompson, Neil Upton

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 333 KB

english, 1999

8

Discovery of SB-705498: A potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development

Harshad K. Rami, Mervyn Thompson, Geoffrey Stemp, Steve Fell, Jeffrey C. Jerman, Alexander J. Stevens, Darren Smart, Becky Sargent, Dominic Sanderson, Andrew D. Randall, Martin J. Gunthorpe, John B. D

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 290 KB

english, 2006

9

Characterization of the binding of [3H]-SB-204269, a radiolabelled form of the new anticonvulsant SB-204269, to a novel binding site in rat brain membranes

Hugh J. Herdon, Jeffrey C. Jerman, Tania O. Stean, Derek N. Middlemiss, Wai N. Chan, Antonio K. Vong, John M. Evans, Mervyn Thompson, Neil Upton

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 327 KB

english, 1997

10

Characterisation of the binding of [3H]-SB-674042, a novel nonpeptide antagonist, to the human orexin-1 receptor

Christopher J Langmead, Jeffrey C Jerman, Stephen J Brough, Claire Scott, Rod A Porter, Hugh J Herdon

Journal:

British Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 163 KB

english, 2004

11

Pharmacology of vanilloids at recombinant and endogenous rat vanilloid receptors

Vera Ralevic, Jeffrey C Jerman, Stephen J Brough, John B Davis, Julie Egerton, Darren Smart

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 209 KB

english, 2003

12

Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid

Christopher J. Fowler, Kent-Olov Jonsson, Anna Andersson, Juha Juntunen, Tomi Järvinen, Séverine Vandevoorde, Didier M. Lambert, Jeffrey C. Jerman, Darren Smart

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 274 KB

english, 2003

13

Characterisation of an endogenous bombesin receptor in CHO/DG44 cells

Stephen J Brough, Jeffrey C Jerman, Frances Jewitt, Darren Smart

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 115 KB

english, 2000

14

Pharmacological characterisation of human 5-HT2 receptor subtypes

Jeffrey C Jerman, Stephen J Brough, Tracey Gager, Martyn Wood, Martyn C Coldwell, Darren Smart, Derek N Middlemiss

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 136 KB

english, 2001

15

Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology

Darren Smart, Jeffrey C Jerman, Martin J Gunthorpe, Stephen J Brough, Jennie Ranson, William Cairns, Philip D Hayes, Andrew D Randall, John B Davis

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 146 KB

english, 2001

16

Cannabinoid activation of recombinant and endogenous vanilloid receptors

Vera Ralevic, David A. Kendall, Jeffrey C. Jerman, Derek N. Middlemiss, Darren Smart

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 148 KB

english, 2001

17

The physiology and pharmacology of the orexins

Darren Smart, Jeffrey C Jerman

Journal:

Pharmacology & Therapeutics

Year:

2002

Language:

english

File:

PDF, 199 KB

english, 2002

18

Low pH modulation of recombinant vanilloid receptors and perivascular capsaicin-sensitive sensory neurotransmission

Vera Ralevic, David A Kendall, Jeffrey C Jerman, John B Davis, Derek N Middlemiss, Darren Smart

Journal:

Autonomic Neuroscience

Year:

2001

Language:

english

File:

PDF, 154 KB

english, 2001

19

Synthesis of Novel trans -4-(Substituted-benzamido)-3,4-dihydro-2 H -benzo[ b ]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile †

Chan, Wai N., Evans, John M., Hadley, Michael S., Herdon, Hugh J., Jerman, Jeffrey C., Morgan, Helen K. A., Stean, Tania O., Thompson, Mervyn, Upton, Neil, Vong, Antonio K.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 119 KB

english, 1996

20

Old drugs with new skills: fenoprofen as an allosteric enhancer at melanocortin receptor 3

Montero-Melendez, Trinidad, Forfar, Rachel A. E., Cook, Jennifer M., Jerman, Jeffrey C., Taylor, Debra L., Perretti, Mauro

Journal:

Cellular and Molecular Life Sciences

Year:

2017

Language:

english

File:

PDF, 2.78 MB

english, 2017

21

Terbinafine is a novel and selective activator of the two-pore domain potassium channel TASK3

Wright, Paul D., Veale, Emma L., McCoull, David, Tickle, David C., Large, Jonathan M., Ococks, Emma, Gothard, Gemma, Kettleborough, Catherine, Mathie, Alistair, Jerman, Jeffrey

Journal:

Biochemical and Biophysical Research Communications

Year:

2017

Language:

english

File:

PDF, 1.09 MB

english, 2017

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